Autoimmune Diseases and Prolotherapy
In this article Ross Hauser, M.D. discusses the autoimmune disorders most likely to prevent Prolotherapy from attaining full healing.
The only diseases that cause inflammation for which Prolotherapy may not be appropriate is the autoimmune diseases, such as Rheumatoid Arthritis and systemic lupus erythematosis. Remember, however, that anyone with these conditions is much more likely than the average person to have poor healing, and thus, ligament and tendon injury and chronic pain. If someone with these conditions has a normal or almost normal ESR, erythrocyte sedimentation rate, which shows that the amount of inflammation is under control, then Prolotherapy is appropriate. This is assuming that the pain can be reproduced by palpation over a ligament or tendon on physical examination.